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Pelvic Pain/ Endometriosis Research

We are actively involved in research to improve the understanding, diagnosis, and treatment of endometriosis and pelvic pain.
Patients are invited to participate in research; your participation may help others with pelvic pain and endometriosis. This is voluntary and greatly appreciated. All of our studies collect information without identifying any individual woman.

Current Research Areas

Endometriosis and Pelvic Pain Interdisciplinary Cohort           (EPPIC) patient registry                                                                       https://clinicaltrials.gov/ct2/show/NCT02911090

Biobanking of surgically excised endometriosis, as part of the     World Endometriosis Research Foundation (WERF)                           Endometriosis Phenome and Biobanking Harmonisation               Project (EPHect): https://endometriosisfoundation.org/ephect

CAPTURE registry for fibroids

Clinical risk factors for pelvic pain and predicting outcomes           after treatment  

Local nerve growth and pelvic pain

Central sensitization and pelvic pain
Gene mutations in endometriosis

Upcoming Event 

World Congress of Endometriosis, May 17-20, 2017,  Vancouver, Canada 
http://endometriosis.ca/world-congress/wce2017
Dr. Catherine Allaire, President


  1. Prospective data collection to evaluate patient outcomes after interdisciplinary care for endometriosis and pelvic pain
  2. Needs assessment survey for chronic pelvic pain among obstetrician-gynaecologists in British Columbia
  3. Prevalence and predictors of musculoskeletal dysfunction in endometriosis and chronic pelvic pain
  4. Predictors of minimally invasive hysterectomy
  5. CIHR Operating Grant to study endometriosis and deep dyspareunia

  1. Banking of endometriosis surgical specimens
  2. Gene sequencing in deep infiltrating endometriosis and ovarian endometriomas
  3. Nerve fibre immunochemistry in endometriosis and chronic pelvic pain
 
Anglesio, M. S., Papadopoulos, N., Ayhan, A., Nazeran, T. M., Noë, M., Horlings, H. M., . . . Shih, I.-M. (2017). Cancer-Associated Mutations in Endometriosis without Cancer. New England Journal of Medicine, 376(19), 1835-1848. doi: 10.1056/NEJMoa1614814

http://www.nejm.org/doi/pdf/10.1056/NEJMoa1614814

Catherine Allaire, Tuba Aksoy, Mohamed Bedaiwy, Susannah Britnell, Heather L. Noga, Holly Yager, Paul J. Yong. (2017) An interdisciplinary approach to endometriosis-associated persistent pelvic pain. Journal of Endometriosis and Pelvic Pain Disorders, DOI:10.5301/jeppd.5000284

Bedaiwy, M. A., Alfaraj, S., Yong, P., & Casper, R. (2017). New developments in the medical treatment of endometriosis. Fertil Steril. doi: 10.1016/j.fertnstert.2016.12.025 https://www.ncbi.nlm.nih.gov/pubmed/28139238

Bedaiwy, M. A., Allaire, C., Yong, P., & Alfaraj, S. (2017). Medical Management of Endometriosis in Patients with Chronic Pelvic Pain. Semin Reprod Med, 35(1), 38-53. doi: 10.1055/s-0036-1597308 https://www.ncbi.nlm.nih.gov/pubmed/28002850

Williams, C., Hoang, L., Yosef, A., Alotaibi, F., Allaire, C., Brotto, L., . . . Yong, P. J. (2016). Nerve Bundles and Deep Dyspareunia in Endometriosis. Reprod Sci, 23(7), 892-901. doi: 10.1177/1933719115623644 https://www.ncbi.nlm.nih.gov/pubmed/26711313

Yosef, A., Allaire, C., Williams, C., Ahmed, A. G., Al-Hussaini, T., Abdellah, M. S., . . . Yong, P. J. (2016). Multifactorial contributors to the severity of chronic pelvic pain in women. Am J Obstet Gynecol, 215(6), 760.e761-760.e714. doi: 10.1016/j.ajog.2016.07.023 https://www.ncbi.nlm.nih.gov/pubmed/27443813

Mui, J., Allaire, C., Williams, C., & Yong, P. J. (2016). Abdominal Wall Pain in Women With Chronic Pelvic Pain. J Obstet Gynaecol Can, 38(2), 154-159. doi: 10.1016/j.jogc.2015.11.003 https://www.ncbi.nlm.nih.gov/pubmed/27032740

Medical and Sexual Issues in Two Common Gynecological Conditions: PCOS and Endometriosis.  Dr. Christina Williams.  Sexual Health 2017.  UBC Continuing Professional Development.  March 31 – April 1, 2017. Vancouver, BC.


Anatomic sites and risk factors for deep dyspareunia.  Dr. Paul Yong.  International Society for the Study of Women’s Sexual Health.  February 23-26, 2017.  Atlanta, GA.  

Pain catastrophizing and endometriosis health-related quality-of-life.  Allison McPeak (supervisor: Dr. Paul Yong). International Pelvic Pain Society.  October 13-16, 2016. Chicago, Illinois


Congratulations to the CPP team and in particular Dr Paul Yong for publishing in the New England Journal of Medicine: Cancer-Associated Mutations in Endometriosis without Cancer, The New England Journal of Medicine, 2017; 376:19                                     FAQs, NEJM article endometriosis-cancer -.pdf

View a detailed list of our publications related to chronic pelvic pain and endometriosis. (Pdf)

FUNDING

1. Canadian Institutes of Health Research
2. Canadian Foundation for Innovation and BC Knowledge   
        Development Fund
3. Women’s Health Research Institute
4. BC Women’s Hospital Foundation


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